Access to Epinephrine is a priority for reducing Anaphylaxis. Intranasal Epinephrine aimed at assisting in acute emergency situations.
Medical need
Definition: Severe allergic type 1 reaction. Life threatening.
Prevalence: 1.5 % of the US population suffer an event each (500,000 cases annually)
Cost of treatment 4 B annually
Mortality rates 1.2 % per episode, 30 % recurrence risk lifetime
Epinephrine IM or IV is the first line treatment.
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